Abstract Submission

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Specify your presentation format:

Case Presentations (Abstract not required at present time)

The abstract should adopt a structured format: Title (block Capitals); Authors names (with presenting author first); author's institutional affiliations; Purpose; Methods;Results; Conclusions and (optionally, Acknowledgements of financial support and the support of any colleagues who are not authors) The abstract should be restricted to 500 words in total.

See an example abstract:

You can type direct onto the form or you can use your preferred word processor and then copy & paste to the box below. It is your responsibility to ensure your abstract is free of typographical errors and is translated in an acceptable English format.

None Financial Support Investor Employee Consultant Patent Gift Recipient Financial relationship (choose a category code from below)

Further details on Financial Relationship Category Codes

ETHICAL ISSUES

The abstract involves the use of human subjects and procedures are consistent with the Declaration of Helsinki.

The abstract involves animal research which was conducted humanely and complied with local guidelines and laws governing the use of animals in research

GRANTS AND AWARDS

I want to be considered for the Eberhard Dodt Award. This honours our longtime friend and scientist. Eligible scientists are 34 years or younger (on 1 Jan. 2005). (Either include this or link to the awards page with this information) The $400 honorarium and $600 travel fellowship may be used for future ISCEV travel. The award is made by an Adjudicating Panel on the quality of presentation as an oral paper or poster.

I am applying for a travel grant. (Further details). In the box below please provide a brief statement of circumstances including an indication of experience in clinical electro-physiology and the reason that financial assistance is required. If you are a student or junior member of a programme, also indicate the name and e-mail address of the laboratory or department director.

* All travel grant applicants must send a separate letter of support (normally from the Department head or director) addressed to:

Prof Daphne McCulloch, ISCEV Secretary General, Dept of Vision Sciences, Glasgow Caledonian University, Cowcaddens Road, Glasgow, G12 0BA, UK

If time is short, letters of support may be sent by fax: +44 141 331 3387 but please also send an original copy by post.

ORAL PRESENTATIONS

Oral presentations will be by Computer projection. Please check the Video projection box if you require the use of video in your presentation.

Video projection required

Please Note: You will receive feedback on submission of your abstract. This will be unformatted text. Do not be concerned by this as your original formatting will be preserved in the abstract book.

EXAMPLE ABSTRACT

USING THE LED MULTIFOCAL STIMULATOR TO INVESTIGATE ‘OFF’ RESPONSES AND RESPONSES TO ‘DARK’ STIMULI OR LIGHT DECREMENT STIMULI.

David Keating 1,2, Stuart Parks 1, Donald C.Smith 2, Aled Evans 2

1. Tennent Institute of Ophthalmology, Glasgow, UK

2. Department of Clinical Physics and Bio-Engineering, North Glasgow Hospitals NHS Trust, Glasgow, UK

Purpose : To use multifocal ERG to investigate offset responses and responses to ‘dark’ stimuli or light decrement stimuli.

Methods: It is not possible to obtain Offset multifocal ERG responses from conventional CRT stimulation due to the short luminance ‘on-times’ for each stimulus frame (typically 1- 2 msec of a 13.33 msec frame update time. A custom built LED multifocal Stimulator was used to provide long duration flashes (106 msec) to enable true separation of multifocal ERG onset and offset responses. The use of light decrement or ‘dark’ stimuli in perimetry for detection of glaucomatous field defects has shown promise in recent years 1 . CRT devices do not allow the presentation of such stimuli. In order to present light decrement stimuli the m-sequence ‘0’ state was set to a 13.33 msec period of high luminance and the m-sequence ‘0’ state set to a 1 msec period of low luminance followed by a 12.33 msec period of high luminance.

Results: Long duration stimuli show clear separation of the onset and offset components with the offset response approximately 25% the amplitude of the onset response. Light decrement stimuli produce much smaller responses with amplitudes less than 10% that obtained with standard stimulation. Waveform shape changes are also present with the relative contribution of the N1 component larger and the N2 component smaller for the light decrement stimuli compared to standard light increment stimuli.

Conclusions: Theses techniques enable the study of offset responses in clinical conditions and are of potential interest in conditions such as CSNB and in Glaucoma.